How does Izzy die in GREY's anatomy?

After speculation that Izzie would be killed off in the fifth season, the character was diagnosed with Stage 4 metastatic melanoma. She married Alex in the series' 100th episode, and afterwards, her tumor was successfully removed.

Does Izzie Stevens come back?

In Grey's Anatomy Season 5, Izzie was diagnosed with Stage 4 metastatic melanoma. ... Nevertheless, Izzie came back in the 12th episode of season 6, where she revealed that she was cancer-free and asked Alex to come back in her life. But by that time, Alex had made up his mind about her and decided to settle for a divorce.

Why did Izzie leave GREY's anatomy?

There was a lot of drama surrounding Heigl when she left Izzie and Grey's Anatomy behind. ... Two years later, Heigl reportedly skipped out on filming before deciding to leave Grey's Anatomy. But, she turned down the rumors, revealing that she wanted to leave the show to spend more time with her family.

Is Izzy still alive in GREY's anatomy?

Fans were wondering whether Izzie died on Grey's Anatomy. But the truth is, Izzie Stevens did not die. Many fans assumed that she is dead, but she is still alive. Fans also believe that she's dead because her character was suffering from brain cancer.

Does Karev die?

While some viewers were happy Alex left without a scarring death, others would have rather seen the character die than to abandon Jo Wilson (Camilla Luddington). ... Recently, Grey's Anatomy showrunner Krista Vernoff revealed why the writers decided not to kill off Alex.

Who does Alex end up with?

Jo Wilson Alex and Izzie's love story seemingly came to an end when cancer survivor Izzie was last seen in Season 6 leaving Seattle after Alex refused to resume their marriage. Alex eventually moved on, marrying Jo Wilson (Camilla Luddington).

What happened to Alex Karev?

Alex went to meet his children, and as Izzie was living as a single mother (and working as a surgical oncologist), he decided to live with them and make sure the kids didn't grow up like he did (in a broken home, without a father), while also admitting that he had always loved Izzie.

Was Izzy pregnant on GREY's anatomy?

At age 15, Izzie became pregnant. She gave birth to a baby girl and gave her up for adoption at 16 in order to give her a better life. ... Because of her pregnancy, mothers made their children stay away from Izzie so she struggled to make friends.

Does Jo and Alex have a baby?

Following her estranged husband's death, she married Alex Karev until he left her for his ex-wife, Izzie. She is now the mother of Luna Ashton.

Does Jo get pregnant in Season 12?

'Grey's Anatomy' Recap: Alex, Jo Baby — Izzie's Eggs in Season 12 | TVLine.

Why did Alex Karev leave suddenly?

After being absent from the show for weeks, it was revealed in the March 5 episode that Karev had left Seattle and his new wife, Jo (Camilla Luddington), to reunite with his ex-wife, Izzie (the character played by long-departed cast member Katherine Heigl), and the former couple's children.

Does Karev have a baby with Izzie?

It turns out they did. They have twins who are five — Eli and Alexis — and he says they are “hilarious.” He went there after Meredith's trial and never came back. The kids both want to be doctors. Izzie is a surgical oncologist, and they live on a farm.